DPCstruct | MC12220

Metacluster Properties and Pfam Annotations

Number of structural domains26
Mean domain length (aa)166 ± 26 aa
Standard deviation of domain lengths25.56
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score84.91
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.87
Mean intra-cluster local Distance Difference Test score0.87
Mean intra-cluster sequence similarity (%)53.17
Pfam Score100.00
Assigned Pfam label(s) CL0065

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1J1IVV6 23-169 ASTSELLKCLGIFLRDRCCKLQDFQAGDAVMWLRAVDRSLLLQGWQDIAFINPANVVFVYMLVREIVDGDETKELDLQAKVLTCLYL…
A0A4U5VUW4 79-256 DVTVAAKKNSLTGSGIQPSTAAGTPKRVIVQASTSELMRSLGEFLCRRCYRLKRLSPTDPVLWLRNVDRSLLLQGWQDQGFITPANV…
A0A1I8IJ35 27-222 None
A0A834Y5Q9 295-469 None
A0A6A4KAR9 9-127 None
T1FXL5 34-184 None
M7CK36 11-184 None
A0A7R8CGE1 23-179 None
T1K2G8 365-543 None
A0A0N4V1U0 25-190 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.