DPCstruct | MC12219

Metacluster Properties and Pfam Annotations

Number of structural domains26
Mean domain length (aa)161 ± 26 aa
Standard deviation of domain lengths26.37
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score77.53
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)30.15
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A498LLS9 2-123 KALCRLTAVARGFLTRRLLQTDKITHLRKTIQDSRDFIRSFQTDSQLKRVSVSHQDLSLYQRVTAQLRSALHDVHQIFIVWPVRDRL…
A0A4U5VU97 42-182 GSKQTSSKAKSGTYAKIDKRVLTAEQQRAFCRIGAIIRGFLTRRLLKTEKVKHLRQTIVDTQEFIRSFKTEGSQKKGTYSAQDRSLQ…
W5M4L6 524-663 None
A0A668RUJ2 1-144 None
A0A5N4A5Z0 249-405 None
A0A5K4FD02 241-371 None
A0A183M4G3 6-226 None
A0A182XX62 2-196 None
A0A6P4K9B0 609-749 None
T1KFK6 216-354 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.