DPCstruct | MC12212

Metacluster Properties and Pfam Annotations

Number of structural domains71
Mean domain length (aa)240 ± 50 aa
Standard deviation of domain lengths50.05
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score91.85
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)17.30
Pfam Score80.11
Assigned Pfam label(s) CL0369- CL0103- PF02884

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A894KF59 378-653 ARKSYHFIDGMIVCLGSDIENTNTEFPTETTIFQLAVTDKAGHDYWKNYQGDKKVWVDHLGTGYYVPTPIRFEKNFPQYSRMQNTGK…
A0A7K2KTH8 6-181 EERTGSWRDINTGGSPDPVTRRYLTLFTDHGVDPAGGAYAYVLLPGASAHATARAAHDRGRLRILANSGARQGIHVPRLGLTAVNFW…
A0A3R8PLA1 21-296 None
F3PP21 658-907 None
A0A7D7WBX3 1-130 None
A0A2E9IMI8 471-713 None
A0A7J9Y5W3 1-134 None
A0A6C2U2P8 1-151 None
A0A5S4EZV4 372-592 None
A0A1G9YTF2 441-672 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.