DPCstruct | MC12196

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)156 ± 21 aa
Standard deviation of domain lengths20.99
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score80.97
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)17.55
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4S2DEJ3 2-137 KNDTAKDWMGDLKHLKLLKYTYKGKIKSEKDKYSVIEATYSDKAPAVSMLPNLVISDTTYTETDMTIHQKIYPQFKIVTVRQMVDAG…
U6RAZ6 1-182 MKYINIVIIFFFISHTVSAQASKTSIYEYGSEIQTCEDNFNNLFRNWTPNIVETANDLQLLSYEFVEELNTSRKIKRDIKWFSNPNT…
A0A4R3KT54 47-226 None
A0A840D6T3 29-201 None
A0A4Q0ME34 1-171 None
R5SX58 1-141 None
A0A412TVI4 1-159 None
I8W1Y7 19-169 None
A0A5B8VNG3 37-166 None
A0A401M004 113-233 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.