DPCstruct | MC12186

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)86 ± 4 aa
Standard deviation of domain lengths4.42
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score90.41
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)44.77
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
F7QWF4 1-81 MSSYPNSREACAYIQGKVVNIVPTNDPNYNDKYNSIYNHGYGEPAGTLGINCRHKLFPFTPGVNVNNMTQYNPKEAIRNGN
A0A5B7T281 19-111 QYKWISTGSWRCKNFPVCALIQGKIVNTVPRTDKHFNPRYPTSYDHGYGYAWGTQGANCRHELYPYIEGVNTNPFHHPDTKKKLKMA…
A0A386PSY2 25-104 None
A0A3S4NCY8 10-101 None
A0A2R3JYJ6 11-97 None
W7C3U7 23-107 None
A0A5C8H7L4 1-81 None
A0A0R2J267 8-92 None
A0A1Q2T4X9 93-180 None
D0DR80 106-195 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.