DPCstruct | MC12173

Metacluster Properties and Pfam Annotations

Number of structural domains34
Mean domain length (aa)190 ± 36 aa
Standard deviation of domain lengths35.57
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score80.03
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)24.84
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A354I2Y8 1-191 MGDVSIKMYDKFGCVLRIESTCNDIGTFRVKRKVEHRDGSSSEQKAPLKKSIYSLYQLFTIMKAANYRYLEFISSFDDHSGGKENLT…
A0A2V8VBK7 18-201 RVTKRLRGKLYSVLEKLDHGHHVMRIYCKNLVGRMYEKFSTFLRVEVCVNRMKDLGLNKGTENLECLRQKLVDITHRFAGFEAQSLN…
A0A498R2F7 176-359 None
Q0S067 89-270 None
A0A1F4DKT8 36-244 None
A0A3D5DYQ3 3-172 None
A0A7Y5SGM3 69-256 None
A0A158EMR6 38-203 None
A0A081HXW5 248-510 None
A0A7V0UIU3 60-255 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.