DPCstruct | MC12165

Metacluster Properties and Pfam Annotations

Number of structural domains90
Mean domain length (aa)146 ± 37 aa
Standard deviation of domain lengths37.41
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score74.46
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)19.13
Pfam Score71.67
Assigned Pfam label(s) CL0123- CL0481- CL0280

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A257N5A5 20-126 KFVPTELLRPVTAQKSERITPEIQESSSEDSPKDFILNALEKICKDGGWTNLANLGNYLTKLKPDFDVRLYGFKSLGAMVKAHKDIF…
A0A373ZDV6 83-216 GIDIVTDDDTILAAVVKAQEQGKNIRVFGSNAHSESFIRRCNRFCYIDILQGYEPEQCLTPLSEIVSDVYRIIIEERASGICTELAG…
A0A1H5T8R6 55-169 None
A0A061QXK4 129-279 None
W7Z8B4 84-234 None
A0A0F9N8U9 91-257 None
A0A5M9L2M2 23-176 None
A0A3L6MYK2 465-565 None
A0A651EEQ6 123-287 None
A0A5N6G266 18-128 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.