DPCstruct | MC12153

Metacluster Properties and Pfam Annotations

Number of structural domains180
Mean domain length (aa)245 ± 51 aa
Standard deviation of domain lengths51.21
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score88.46
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)17.75
Pfam Score92.97
Assigned Pfam label(s) CL0704- CL0245- PF02734

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2T6E4J1 5-250 LITDPTCHLPAGALKRFPIDRLTPSDTFDERLSEQWLYHCDALLGIGSTLSIESWQTVIAQRHDELSPRRLSAHLRTPFYVRLFHSQ…
A0A6N2TXZ0 6-280 AFISGGGGGHEPLDSGFVAPGMLHACVTGPRFTSPSAPDIAQLMEEVTAELGVNTIVALVKNYTGDVMNFELAAELAAASGLECIMI…
A0A4U0VQW4 39-378 None
A0A811MH20 234-450 None
A0A6A4H208 36-391 None
A0A327VF71 21-237 None
A0A1A9X9T2 134-306 None
A0A6B1E3Y9 61-340 None
A0A3M1BR21 13-228 None
K8FCA7 320-705 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.