DPCstruct | MC12143

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)251 ± 19 aa
Standard deviation of domain lengths18.61
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score79.31
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)31.10
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A430KZ58 7-272 GALVHATARGRPEAYMKWIVMKYAEMLIAAGDAHFRQGTLESLPLAIQRYVEAGHILGPEPPKVPKLGNKKPRTFANLSQEDAQLEL…
A0A3S4CUI4 71-323 SVDPDAVAQNDPMHYKVSTLMKLLDLLIARGDSAYRMLERDTLNEAKMWYMQALGLLGDKPLTTISGAWSNPALSDAADKTQAKQFH…
A0A2X4T5F1 243-493 None
A0A849EWZ7 274-542 None
A0A7Y5J661 138-414 None
A0A0L0JGV6 81-346 None
A0A4D7JGN6 466-717 None
A0A3Q9D790 125-338 None
U1HTU8 337-606 None
E5ARL0 150-408 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.