DPCstruct | MC12085

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)159 ± 16 aa
Standard deviation of domain lengths15.90
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score66.21
Mean fraction of residues predicted as intrinsically disordered0.93
Mean length-normalized TM-Score0.33
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)33.18
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Z0M899 162-315 LPDAAGVGLPGGGEILTTAEQVAILDAQLDQGTAVFDDMILDEQEKQRSSARDNASAAQDAARNTPARHEPYENAVARKDGGLYGST…
A0A3D0GNG2 1-134 MLDAELEATTSVFDQIIRSTQDQQRNEARTQSPATDLEVEPATESSNESYGAMPGRSAGSGAGGAPGAGGGMRSGQPASTAATAQYP…
A0A2A5WWP7 143-283 None
A0A4R5LQR9 224-378 None
A0A661G7X8 23-197 None
A0A0S8BRN9 98-261 None
A0A2W4MXD3 1-171 None
A0A2D5QGY7 67-224 None
A0A831ZHB6 19-197 None
A0A1E8CL86 92-271 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.