DPCstruct | MC12078

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)227 ± 16 aa
Standard deviation of domain lengths16.23
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score66.42
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.41
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)32.99
Pfam Score86.11
Assigned Pfam label(s) PF15024- PF15027

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6I9MER9 1-225 MEELLKLQLEKDEKKIQQFKSVPPPPPLKDCKAEMQLFQFQIESEKEKGKLKDEMIKDLRADKLRLHLAHKEKAPPLMKKKEEMVEK…
A0A4E0R5L7 1-250 MIALPDTELRANILRLSADYVRLLAREQQDTADGPYRSLGTNYDMKKTMAVLLNEMNIRVEQLDAQVKELSARVTGSGTESRSLSPS…
A0A5C6NU35 2-198 None
A0A673Z4S2 48-275 None
A7RGB4 42-267 None
A0A673D0S9 4-243 None
Q4SSE2 43-284 None
R7T9E6 44-284 None
A0A401NPL5 43-260 None
A0A4W4HB08 15-249 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.