DPCstruct | MC12064

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)155 ± 11 aa
Standard deviation of domain lengths10.64
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score80.29
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.85
Mean intra-cluster sequence similarity (%)53.51
Pfam Score100.00
Assigned Pfam label(s) CL0220

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A821CCM2 285-422 QDMDYILNCVDINQDGKIDFMEFTERFHNPARDIGFNMAVLLTNLSEHMPHDIRLQRLMDKGKSFLSYFQDHLGRIEIKGGAGYIER…
A0A2H1CNV6 6-158 EEISYIIACVDTNADGKVDFKEFTERFYNPAEDIGFNFALLLTNLSEHVPFDPRLERLVEKARGVLDVFEPHLGRIEITGSNGRIER…
A0A821JZC0 110-266 None
A0A3B3INL7 50-231 None
A0A7J6PI07 206-364 None
A0A6F9CKB1 10-174 None
A0A2R7WGW6 415-570 None
A0A834DAY0 108-274 None
A0A1Y3EPZ2 2-154 None
A0A1S3T2W2 229-377 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.