DPCstruct | MC12062

Metacluster Properties and Pfam Annotations

Number of structural domains36
Mean domain length (aa)281 ± 60 aa
Standard deviation of domain lengths59.96
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score80.42
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)31.91
Pfam Score100.00
Assigned Pfam label(s) PF08326

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H1CLR2 153-379 LEPALAFQLELNRMRNYELEQLPCLNRRMHLYLAKSKASCSTFSPLLQFSCYYFLTFFVRCIIRHADLLSREASFEFLQSEAERTLL…
A0A1W9VDC7 5-377 IMGRRFNRDRDFERGKLLGKNGLNAYYCESGNLDIDLLHKEITTVLKESDLKDSLICDLADLSGAEEDLSINLIILSERKADKDYLN…
A0A2T6ZQT5 522-740 None
A0A821UC68 221-501 None
A0A7R9A190 267-563 None
A0A836AMR0 406-631 None
A0A0U0WC58 101-473 None
J9EE75 84-282 None
A0A1S3J5V5 20-294 None
A0A0C9VFA2 133-560 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.