DPCstruct | MC12054

Metacluster Properties and Pfam Annotations

Number of structural domains48
Mean domain length (aa)122 ± 14 aa
Standard deviation of domain lengths14.30
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score85.84
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)15.70
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A662RS66 4-109 RRVLWLSRHEPQEKQIKELEKVFGGIEIVQVSKTVSGAMEVLKLMQENETDELVAVLPIGLIAELTEKGVHPLRAVMKRELNEQGEA…
U2UNB5 1-121 MERCFLNHTNHPSDRWGKEQMRAASSYGVVEDLPFPAVLPGWTTEQVDALAAAYAARILDREPAAVLCQGESCYVFSLVTRLKAAGI…
A0A3R9RUE0 1-138 None
A0A8B2DG47 588-704 None
A0A2J6IG67 1-97 None
A0A7U6KKD0 288-392 None
A0A6M3K256 2-165 None
A0A2H0YQ78 2-113 None
A0A7Y5V227 1-120 None
A0A2N3G5J3 165-277 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.