DPCstruct | MC12035

Metacluster Properties and Pfam Annotations

Number of structural domains48
Mean domain length (aa)82 ± 11 aa
Standard deviation of domain lengths11.39
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score83.96
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)41.88
Pfam Score92.39
Assigned Pfam label(s) CL0023- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A075FKN1 4-84 VKSDIEIARAAKMEPIKDVLAKLNIPDEPATFSPMGRHIAKLNLEYIDKIKAKSNNLILVSAITPTPAGEGKTTTSVGLCD
A0A425DER6 10-108 AAGRFRALSTWHLKRLPLQVQVPTPCDGVIASAQTPKRIETLAAEIGIDAADELKTYGPFKAKVSLDVLKRLHHQPNGKYVVVGGMT…
A0A0D8XA69 73-162 None
A0A6S8SSP5 365-435 None
A0A540K4L6 9-106 None
R5Q2S8 4-69 None
W4UC10 4-103 None
A0A257JC61 3-71 None
A0A3Q7X2M7 237-312 None
H3AAF4 2-87 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.