DPCstruct | MC12023

Metacluster Properties and Pfam Annotations

Number of structural domains3
Mean domain length (aa)78 ± 1 aa
Standard deviation of domain lengths0.94
Length coefficient of variation0.01
Mean AlphaFold2 pLDDT confidence score71.12
Mean fraction of residues predicted as intrinsically disordered0.37
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)51.30
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
F4X8G3 353-431 LERQSAGCSSASGSSSASPSPGPAGPRFKPLEEGDIQVCYLNHTRTLVKKILSSKFLRRWETHHLYLNDACLSSKTVSV
A0A7R9KQD0 84-160 VDEGVFHSTCNSPAKSIPSSPMGPKFKLIHEGDIHLCRLNHQRTVISKILSSKFLRRWESHRLYLTAVNITSKTVCI
A0A194PQ74 216-292 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.