DPCstruct | MC12019

Metacluster Properties and Pfam Annotations

Number of structural domains19
Mean domain length (aa)63 ± 11 aa
Standard deviation of domain lengths10.59
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score75.80
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)43.95
Pfam Score100.00
Assigned Pfam label(s) CL0029

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H9ISF6 25-81 KPLKVNREIAGLERLIEELHGIFSRSHVNVQDVQKLMAGYKSDPKDWRKYAKFDRFR
A0A5E4QTT5 31-83 KVDIEIPSLKILIEELHRVFENNYVNIQHVQKLMAAYKSNPKDWKKFAKFDRY
A0A833RW28 83-139 None
A0A7J7XYQ4 2-56 None
A0A7J7XY25 2-76 None
A0A443SSU6 2-58 None
A0A7R9QPX9 1-59 None
A0A401KS74 1-89 None
A0A3Q0JIQ3 70-136 None
A0A7R9HRN4 37-94 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.