DPCstruct | MC12014

Metacluster Properties and Pfam Annotations

Number of structural domains134
Mean domain length (aa)244 ± 44 aa
Standard deviation of domain lengths44.37
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score86.69
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)21.43
Pfam Score87.78
Assigned Pfam label(s) CL0039- CL0235- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2Z7A2D6 2-275 SKILVIAEHLDGKLNPSTARAVSAAAAVKPEAVDVLVLADNAAAIAAEAARIGGVSRVLTVERAENAHPLAAVLAPQIAKAAAGYSH…
A0A837U159 1-181 ATEVIAVSVGVTQAQETLRTALAIGADRAILVESNDSVEPLAVAKILKALVDKEQPQLVILGKQAIDDDSNQTGQMLAALAGLPQAT…
A0A0Q4B792 19-200 None
A0A1S3G323 59-311 None
J4UGW4 19-315 None
A0A2V2E5V5 9-213 None
A0A7Y0N5V7 71-340 None
R7TU78 1-215 None
A0A2R6FL14 169-532 None
A0A538Q374 9-223 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.