DPCstruct | MC12009

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)427 ± 34 aa
Standard deviation of domain lengths34.15
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score81.26
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)15.74
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3D4NQB7 1-481 MRIDSTWHASVGGLLFQVSIETGFGDVYLVDPERPHHPGFKLASDGQGHWRLDRGARLEGGMPRERVQRWKDANQIHLDALTAQAQQ…
A0A449IN61 3-370 GEGLYPVHIDSEDNVAISSNTDINRIGPNLRTDGKGNWFVDTRLRLQAGGLSRRIASLQAQKARRKSELQTQLTDFYPLEAPRQKAV…
A0A2W0ERT5 2-409 None
E0WSL0 194-622 None
A0A1H1ZNB3 533-966 None
A0A1N7U7M4 205-570 None
A0A2N5EXZ3 361-799 None
A0A6L5I8M7 174-623 None
A0A7C8XN70 19-460 None
A0A3C1AJK3 386-848 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.