DPCstruct | MC12000

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)71 ± 8 aa
Standard deviation of domain lengths8.06
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score87.13
Mean fraction of residues predicted as intrinsically disordered0.54
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)42.97
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A023X7W1 6-75 LKGVQLVVRDIRAARAELVGRGVEATEVRVLRSSGARPAKDDEDLNNVGFVFFSDPDGNGWAVQEINVRR
M3BZ50 4-76 LPEPGGAEACRYLRERGVETVEIFHDTSDVFHRSSGATRRPGPDPERRTYRSYAVFNDPDGNEWVLQEVPAES
A0A5M3VWQ7 45-115 None
A0A401MTK4 1-59 None
A0A7K3EV83 1-69 None
A0A1L5NWW7 26-91 None
A0A081I223 361-435 None
A0A120FIM5 10-60 None
A0A1G8G687 42-127 None
A0A810M7Q6 251-322 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.