DPCstruct | MC11978

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)268 ± 14 aa
Standard deviation of domain lengths13.61
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score89.73
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)34.16
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0X3BIM4 1-236 MTDIYIDGDVALNHGSAGLGSSEEPGSIQINGDLELWNGARNIYGDVYVAGNFSLKDARIHGNVYVDGNLTLGWTPWIADDAHIYYT…
A0A7K4DHY5 54-321 SGGNVNGPGATVIITGGLVTTDANQGASINVSNIYFDGDVTLSSGSASLGSRDEPGSIYINGSLTLRNGQRHIYGDVYVNGNCDLGS…
A0A3D5NSE8 3-264 None
A0A3R7VQI3 190-464 None
A0A265Q8A8 530-802 None
B0TDZ5 361-636 None
B1I3F1 282-550 None
H1YWB1 852-1121 None
A0A6F9WZK7 53-343 None
A0A1M5RHU1 173-429 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.