DPCstruct | MC11973

Metacluster Properties and Pfam Annotations

Number of structural domains33
Mean domain length (aa)145 ± 13 aa
Standard deviation of domain lengths12.61
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score83.02
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)41.88
Pfam Score95.00
Assigned Pfam label(s) PF07795- PF01992- CL0475

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H3H3N0 1-121 MRISDRTPLYPSIGTLYPDATAILAEAGDESALGAALDPFPVYRKIWEVHQGEGVDSKSIDDAFYERDVQMAELAFQSQMHFACFYA…
A0A3L7HFW3 16-157 PILEFEADRRTFIITINSFSTELSKEDHAKLLPHCGRRYPEGLAQLARADDYEQVKNGADYYPEYKLFFEGAGSNPGDKTLEDRFFE…
A0A816NJT0 518-668 None
A0A0A9X4U3 1-124 None
A0A812DKV2 339-489 None
A0A813FMR1 596-748 None
A0A4V3WIS0 201-349 None
R7QLV0 298-447 None
G1T239 391-541 None
A0A7J8C0Y2 45-187 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.