DPCstruct | MC11966

Metacluster Properties and Pfam Annotations

Number of structural domains86
Mean domain length (aa)153 ± 17 aa
Standard deviation of domain lengths17.42
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score80.79
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)24.16
Pfam Score72.11
Assigned Pfam label(s) CL0123- CL0608- CL0063- CL0667

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7Y5RSS6 17-184 NHHSIAEPTIVAEAYDRVSGDRLKLFLTLDDKDIIEDAGYRIEGNQTCLASTSLLSELLLNRHMEAAAKISPDQLRAGLDELPEEQL…
V6KTJ5 127-284 EPLRLRSAVVDVACLGEPDAAEGPGVRQITLTDPGRNRYARLAVRDDKIVAAVLVGLPQAIATLGLLHRRGQYLPADRLGLLLDLPA…
A0A7Z7IYV5 182-326 None
A0A377DLR7 130-294 None
A0A251XSL9 40-188 None
A0A3E1RA76 419-556 None
A0A517SRM8 144-302 None
A0A7Y5T5A0 47-205 None
A0A0K2RFC3 3-114 None
A0A5C7N2P0 794-947 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.