DPCstruct | MC11961

Metacluster Properties and Pfam Annotations

Number of structural domains75
Mean domain length (aa)409 ± 62 aa
Standard deviation of domain lengths61.71
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score88.75
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)19.88
Pfam Score68.97
Assigned Pfam label(s) PF07624- PF07626- PF07637- PF07583- PF07627

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J5EX76 303-725 VAANEIAQVVRQRRADVVACSPTDGSACGAEFIAQYAPRAYRRPLAPSEQAALQQVFDAYLAQDGFDVALELTTQVILQSPAFLYRV…
A0A2E4GLY1 51-422 IDAFVKNRLKKQNIEPSPLSDRHTLIRRLHFDLIGIPPSHEEVKDFAYSDDENSYPKLVERLLNSPRFGERWARHWLDVVRYAETNG…
A0A7W0QBV7 31-326 None
A0A4Q5X354 114-550 None
A0A4Q5X6C0 69-385 None
A0A4Q3JSY5 8-353 None
A0A1Y6CDD0 213-619 None
A0A800JJF4 1-288 None
A0A1P8WEV3 634-1115 None
B4D224 614-1020 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.