DPCstruct | MC1184

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)81 ± 7 aa
Standard deviation of domain lengths6.95
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score78.59
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.89
Mean intra-cluster sequence similarity (%)62.01
Pfam Score100.00
Assigned Pfam label(s) CL0154

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A452EYD2 103-179 KESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKAGVDGWFKLLSQEEGEYFNVPVPPEGSEGNEELRQKFERA
A0A3S5BW66 1-85 MSKRVAIELWDWDRTSRNDFMGSLSFGVTELMKTPITYAWYKLLTQEEGEFYAIPCVDEASAAMAELREKIKILRRSESTKNLYK
W2SPA9 43-130 None
A0A183K928 226-321 None
A0A183WM22 22-110 None
A0A194Q0Y7 146-222 None
A0A444UNP5 140-215 None
A0A3Q1BJ72 204-279 None
A0A7R8WII0 212-283 None
A0A2P4WRA2 381-458 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.