DPCstruct | MC11774

Metacluster Properties and Pfam Annotations

Number of structural domains49
Mean domain length (aa)210 ± 26 aa
Standard deviation of domain lengths25.64
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score70.92
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.39
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)36.02
Pfam Score100.00
Assigned Pfam label(s) PF12317

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q9VJ72 164-413 TLPMRGSASGAGRSKRQDDQSFIMSADKWEDLSVPGELKELFPYIVKYTPQTIDTPFHLQPFIPEFVPAVGDVDALLKVQAPPLLQP…
A0A3P7Q8P9 39-236 KSSIDDIEIFEYINAYKPENIEIKFLLKPFLLDYIPAIGDVDTFIKIPRPDGDNLGLTVLDEPAIQQSDPTIVGMQLRNECKEIKTE…
A0A3P7HF70 56-281 None
A0A2R7WH58 61-233 None
A0A1I7V6H4 50-223 None
A0A7S1SL40 13-216 None
A0A2A4JU25 285-521 None
A0A4Y7LLR3 18-208 None
A0A397F651 449-680 None
A0A177WK28 239-430 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.