DPCstruct | MC11706

Metacluster Properties and Pfam Annotations

Number of structural domains75
Mean domain length (aa)142 ± 22 aa
Standard deviation of domain lengths22.15
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score83.84
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)34.03
Pfam Score99.35
Assigned Pfam label(s) CL0261- CL0072

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D7FYW6 2-137 LLEHTTDIYDGVTVDGASLPATTEEFKSVLEASLEAWRSTGKKGVWLKVPADRTELVPVSIDLGFELHHAEKAYIMLNMWLPSTASQ…
A0A446YPI7 16-156 MTKNGGDVELLPFVYDKHGGIIIEMTSPMDPQAFSASLKSLLSKWREQGIRGVWIKLPISLANLIQSAVEEGFWYHHAEETYLMLAY…
A0A834WW98 289-453 None
A0A453SIH4 24-183 None
A0A067KNC4 60-175 None
A0A158QYM5 3-138 None
A0A0D3DM40 2-124 None
A0A5A9NKM7 32-174 None
A0A6P8HLI4 6-173 None
A0A1B0AE84 74-231 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.