DPCstruct | MC11648

Metacluster Properties and Pfam Annotations

Number of structural domains4199
Mean domain length (aa)184 ± 45 aa
Standard deviation of domain lengths45.12
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score83.14
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)20.69
Pfam Score90.67
Assigned Pfam label(s) PF08352- CL0110- CL0177- CL0202- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A221BRP4 17-230 VLKNINVQVKKGEVVVVVGPSGSGKSTLLRCINQLETITDGELIVQNTEVHNAKTDMNELRRNIGMVFQHFYLYPHKTVLQNITLAP…
A0A7I7ZYD5 16-177 RPALDNVSLKIDKGEFVFLIGPSGSGKSTFMRLPAVRGADVAFALEVIGKRPDTCNRIVPDVLEMVGLSGKANRLPGELSGGEQQRV…
A0A538QC60 663-880 None
A0A0D9XS69 27-178 None
A0A5B7DHR4 175-309 None
A0A6B0DV10 284-500 None
A0A2G2QXL3 349-570 None
A0A5N6ET59 14-228 None
A0A2G4IXB4 69-231 None
A0A6L7A871 8-150 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.