DPCstruct | MC11623

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)187 ± 15 aa
Standard deviation of domain lengths15.11
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score78.32
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)39.14
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D8SN07 33-218 ENSSSNPVAKLVSSLPIVGLFMRILSDEGGIGGDRVDFPDFYTRVQKRCPEDASGAFARFVERHGKVAKPMFVLVWCWVAAVGAGLL…
A0A2P6VSD2 1-184 MAKRAVGALPIIGLISRLTATEGGIGNDAQAYPEFCRQVFDAAPQGFQIAVAELQDRHGKAAQRKYVLLALWMARHGGGIVPGKAIV…
A0A699GH73 597-777 None
A0A7S2Z0A0 68-252 None
A0A6A6M9C2 1-172 None
A0A835UBB2 1-166 None
C1E2D8 2-168 None
A0A7J0FBD8 3-189 None
A9NNS3 65-262 None
A0A0E0L4U8 90-280 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.