DPCstruct | MC11576

Metacluster Properties and Pfam Annotations

Number of structural domains35
Mean domain length (aa)132 ± 16 aa
Standard deviation of domain lengths16.01
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score87.64
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)15.88
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7W1HFX5 7-145 WHQIIIDDPACLPGKIIYDVIQVLLCKIEFKYVVLDDIEGAAQKGLIPILRGMENSVLELDEFMSIVREVQQFDFGDFFLFKEYPKK…
A0A8B0IDK5 3-135 KIEIYGQDKEELSIDLEQVVQPIQTIEGYSWKILWIDGESETDEYSVFELQEVIDQQDGIIVDYEALVNLSHKMETVTEALIIGDRN…
A0A2D7NM38 67-213 None
C2UAG7 1-115 None
A0A351L1Z5 2-125 None
A0A5C6ATH6 41-187 None
A0A1I6X628 2-116 None
A0A3R8MGN8 72-184 None
A0A7W5VAT9 13-133 None
A0A7U0A328 6-154 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.