DPCstruct | MC11472

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)132 ± 12 aa
Standard deviation of domain lengths11.85
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score67.26
Mean fraction of residues predicted as intrinsically disordered0.42
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)45.68
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A445BRU5 21-142 VEVENRREVRLQPGAEEKLVLQFMDSLNSYLSLSHSLSSTLGQAWMELASARHSMGTARLNTSLLDLKFHPASTTLKITEYDVDLVD…
A0A368UGG6 1-127 MEKINKLQHQCQVPRAEEKFVLQFMDSMDNYLSLFDAVSSTLRQGWFDLASARHSMGASRINSSLLDLKFHSAATTLKITNYDGTQP…
A0A6A1UWR5 35-187 None
A0A5C7IVJ2 177-305 None
A0A1P8ASF3 1-133 None
U5D9X3 1-113 None
A0A498KHH7 41-183 None
A0A7J9DFY6 143-262 None
A0A6N2LFY5 11-139 None
A0A6A3AMS1 1-146 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.