DPCstruct | MC1141

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)154 ± 25 aa
Standard deviation of domain lengths25.17
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score81.42
Mean fraction of residues predicted as intrinsically disordered0.45
Mean length-normalized TM-Score0.35
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)21.27
Pfam Score33.33
Assigned Pfam label(s) PF15584- PF18426

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
K9DHI4 249-426 TTLREGRRQLNGWEGEEILTRRPEYKDDTDAHEFRFFSVGQRHDALHPLLDIRMDTGVKENARASVRPSLTDEAALALWDKLLPTIR…
A0A8A8M7J2 1-131 MNSGEEIPVEGIWEPWFPGDEVGCPNYFLKGSIAHQYLLEGTNDEYDVRWRLLWEDTRYQGGSIPEEESTYFPKPVAETSLRALPGE…
A0A375C5Q8 1-179 None
A0A0M4LDX1 105-238 None
A2W084 429-576 None
A0A7U5XV98 2-177 None
A0A4R6DWI8 331-443 None
A0A4R6DWG6 181-316 None
A0A2V4UQF7 176-303 None
A0A2G8TF23 163-338 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.