DPCstruct | MC11380

Metacluster Properties and Pfam Annotations

Number of structural domains29
Mean domain length (aa)411 ± 63 aa
Standard deviation of domain lengths63.05
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score76.82
Mean fraction of residues predicted as intrinsically disordered0.59
Mean length-normalized TM-Score0.37
Mean intra-cluster local Distance Difference Test score0.85
Mean intra-cluster sequence similarity (%)23.80
Pfam Score88.24
Assigned Pfam label(s) PF10375- PF13851

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1X2GDU2 3-283 VNDLSAELDMTKTQLDEMRSAMVTRDQEANQQLDAKEKTVVQLQRHVETLQGERDELEMHAMDLDARCHQIQEEYEANLAELTRCKK…
A0A1S8B6Z2 3-356 QDAEELDRMRTQVDDLEDQNRQLRDDNEQLRKQTEEHASEISSLRSRATLSQQNWVKERDELIQREAYAREEFETAKQAMQDWEVLA…
A0A0H2S527 1-357 None
J6EM82 21-435 None
A0A0C9V577 16-404 None
A0A1G4KF80 1-446 None
A0A0L0TA08 48-355 None
A0A2Z6NXS2 35-621 None
S2JIT2 241-623 None
A0A0C7NCK8 30-448 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.