DPCstruct | MC11374

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)197 ± 19 aa
Standard deviation of domain lengths19.08
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score74.93
Mean fraction of residues predicted as intrinsically disordered0.54
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)25.96
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6S8UYW8 1-183 MKENLNLACQKQHDASTASSDSFLLLAAKKNDRDVCQTHEKAILSEFLNAVPKQHQFHKPLLKVFSKKLKRSKKNISGNTSEDETNE…
A0A6I8NLG9 146-336 VEQEILKREEIRNLYLQEHLNRRWKLEDFLSEMEDKKLEMTRLQDQEKALYASFQASLGENNSFASFLTKVLKKKIKRVKKKETEGD…
A0A3P7LN29 2-166 None
B4Q353 227-446 None
A0A4Y2IWE5 36-221 None
A0A7S0AGE2 77-295 None
A0A3P8GUF6 82-304 None
D0P440 41-223 None
A0A4C1XKY6 2-183 None
S8ERJ9 438-628 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.