DPCstruct | MC11356

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)139 ± 25 aa
Standard deviation of domain lengths24.95
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score77.64
Mean fraction of residues predicted as intrinsically disordered0.54
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)36.56
Pfam Score100.00
Assigned Pfam label(s) CL0306

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A821L5I4 1-108 MNVPADNVKIQTTLRQLEQPMCLFGEGPAERRKRLQNLISSLSDNEIAKILPWYHDGPDELQTVRYWIAEYSLSRAKERIEKLKEYV…
A0A0C4EJT3 2-175 EVDFDDLVTKQFDPNDPNQTRTQAEHAALLTSLDRATRSRQLAVPTNEVAIRVRLRELGEPMTLFGERPEDRRDRLRYVLSQIAEAK…
W2T3T4 28-184 None
A0A812IQG1 2-105 None
H0ERL8 533-665 None
A0A4Y9Y8V8 3-162 None
A0A183R482 1-189 None
A0A821UCN2 9-122 None
A0A1X7SFZ7 12-144 None
L2G8P9 417-558 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.