DPCstruct | MC11352

Metacluster Properties and Pfam Annotations

Number of structural domains2194
Mean domain length (aa)148 ± 25 aa
Standard deviation of domain lengths25.41
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score77.93
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.32
Mean intra-cluster local Distance Difference Test score0.47
Mean intra-cluster sequence similarity (%)12.36
Pfam Score89.49
Assigned Pfam label(s) CL0489- CL0003- CL0652- PF20636- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H0ZAQ3 260-371 None
A0A139W9N2 62-197 None
A0A264YXR4 25-196 None
A0A2E3MTC2 140-260 None
A0A2E3MQ78 185-313 None
A0A3Q4HZZ7 1-145 None
A0A5R8PDZ1 3-140 None
A0A835NWE4 576-733 None
B4D9Z2 126-287 None
A0A4S4ESB2 203-362 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.