DPCstruct | MC11352

Metacluster Properties and Pfam Annotations

Number of structural domains2194
Mean domain length (aa)148 ± 25 aa
Standard deviation of domain lengths25.41
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score77.93
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.32
Mean intra-cluster local Distance Difference Test score0.47
Mean intra-cluster sequence similarity (%)12.36
Pfam Score89.49
Assigned Pfam label(s) CL0489- CL0003- CL0652- PF20636- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1D6IZB0 94-267 None
A0A7S2DUP1 1-131 None
Q385M1 259-414 None
A0A6P3ZZ20 4-197 None
A0A7G2FJ32 122-264 None
A0A7S3GTC1 2-136 None
A0A818SJ48 68-239 None
A0A250XV69 9-144 None
Q3LHL9 1101-1290 None
A0A317KSY6 70-201 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.