DPCstruct | MC11352

Metacluster Properties and Pfam Annotations

Number of structural domains2194
Mean domain length (aa)148 ± 25 aa
Standard deviation of domain lengths25.41
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score77.93
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.32
Mean intra-cluster local Distance Difference Test score0.47
Mean intra-cluster sequence similarity (%)12.36
Pfam Score89.49
Assigned Pfam label(s) CL0489- CL0003- CL0652- PF20636- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A445N4A5 18-168 SIFDQAVSSQDTWEMYLHKFRVIKAKLIENLKYDIKIEIKDLGNEVIPKVNIKMLYPLTQAETVSGLIKTDDKVKDLNLEPILAPAK…
A0A1S7LFB9 10-145 VVKRSLKNRQHIRYYTEKDNIETSARVLKVGAKYAEVEDLEGGACWKVPFYMINLQGVEVDIHVSEPGVKLDKNLLKNGEFVGFFDN…
A0A3L7PM48 109-231 None
A0A068V5I9 72-206 None
A0A6D2HLC0 3-140 None
A0A068V7W8 75-190 None
A0A810LB07 3-161 None
A0A0E0H906 225-364 None
A0A1G4T7K9 61-205 None
A0A3S1A6C3 161-345 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.