DPCstruct | MC11337

Metacluster Properties and Pfam Annotations

Number of structural domains41
Mean domain length (aa)146 ± 17 aa
Standard deviation of domain lengths17.45
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score83.96
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)23.75
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A848S8Q3 1-116 MLHELHKVGYQRLRADMGMSPSGMHWRCKIFVVDRPGIEPAYYTSADKTNYYRWTDADQDTARQMAAKFIYRFPELCEAGTGLDFAN…
A0A3G8Y3V6 3-128 KLLHLAGELHRKGYTGLQVIPSLSPSCVYWRCDFTNADSSERLSVSNWLQENFDIKEKEASTTEIVKRFEEDYNHFLLGSQGKDEYY…
M7MU35 6-161 None
A0A7C9KX95 2-152 None
A0A6G6W9Y9 298-459 None
A0A2M6V8J6 353-499 None
H5YLL9 8-173 None
A0A2D5S7U2 148-308 None
A0A220UCP8 2-129 None
A0A6L6FYH6 14-132 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.