DPCstruct | MC11253

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)262 ± 23 aa
Standard deviation of domain lengths23.22
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score86.23
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)40.49
Pfam Score100.00
Assigned Pfam label(s) CL0137

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2U1LXU9 2-253 FKSVVVLYEGEKMLGNVDVSFTPENFRVLRHKISGKVVVSHLSKPSERCSPLAVLHTITSSGNGRRNGVCLKMECRDTSNHWMHFLY…
A0A2I0J6C2 7-246 KCVVYHGETCLGELDAIPVSDQGFQFPGNEIRIHHISPHSERCPPLSVLQTISSFSVRCKLESSFPGEQSHLINLHASCFYECKTAV…
A0A453FYQ1 11-256 None
A0A4S8J5T3 1-318 None
Q5N890 1-270 None
A0A540L471 7-246 None
A0A2P6V3X3 1-269 None
A0A2C9U4Q6 3-260 None
A0A833QFQ2 3-244 None
A0A7S3QXX6 2-292 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.