DPCstruct | MC11232

Metacluster Properties and Pfam Annotations

Number of structural domains194
Mean domain length (aa)118 ± 15 aa
Standard deviation of domain lengths15.34
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score86.82
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)20.99
Pfam Score63.89
Assigned Pfam label(s) PF11807- PF03951- PF06209- CL0286- CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0D2QTE6 4-113 LTDLVNLNLSDCTDKIIAEYIWIGGSGMDLRSKARTLSGPVSDPSKLPKWNYDGSSTGQAPGEDSEVILYPQAIFKDPFRRGNNILV…
A0A063YPU1 6-117 VSSTQTELLEQIKEKIKEKNVELLHLQFVDIEGILKHVTVTAEQLDDVVEGKIMFDGSSIKGFSPINRSDLYLLPDLNTFAVLPWTV…
A0A2H3C3J4 15-146 None
A0A446IT65 164-291 None
A0A0H2M766 472-602 None
A0A4Y7L0F7 128-268 None
U6KMD9 41-154 None
A0A7M5X9Z2 19-155 None
A0A815T6D4 314-440 None
A0A7J9KQK4 30-156 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.