DPCstruct | MC11187

Metacluster Properties and Pfam Annotations

Number of structural domains28
Mean domain length (aa)119 ± 12 aa
Standard deviation of domain lengths11.60
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score79.73
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)34.76
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7C1U4E2 12-150 LLAAGLASLGLPLAVQAEVPLPKVPEAQKRVSETQGCVEPVEVMRKKHYEFLKHQRDDTLRRGIRTRKYSLEECINCHVPPPESGKL…
A0A3B1CJR0 8-112 IASVLFLIILAFPLYYNVFAGAPPAPEIKVDKPGKCIAETSWMRSNHMKMLMHTRDNVVREGFRETNHGIQGCRSCHEKRSEFCDKC…
W0SDD2 38-164 None
A0A661DL84 32-156 None
F8AAJ0 1-123 None
W0DJS3 15-137 None
A0A0S8CS13 5-125 None
A7BPV9 22-139 None
A0A3B0YKX0 16-150 None
A0A1E5Q9M9 2-105 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.