DPCstruct | MC11177

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)209 ± 19 aa
Standard deviation of domain lengths18.91
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score85.77
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)13.40
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
X6BT53 84-289 YESIHRRIAGKGGLDKAIYAEFAGAWNAVTHRFKALVTHDDLFTASISKHGTAPPAEERHNQERDLFGFFNSGFSMFEAFFYALHAA…
A0A7C1VHZ0 8-213 ELRKLCKEKGIPDSTLYQNSLGWRWKRTDFHADKANEVWAELFMKSFTFVDQRCYEAIFSYEAHVESCVQSLHSMADILAQIINVII…
A0A8A5Z5J2 26-208 None
A0A164QF00 41-243 None
A0A6M6E311 12-203 None
A0A1Z4KD60 9-247 None
A0A4Q3F9V9 58-238 None
U5F8H4 191-404 None
A0A6M6E8F3 16-226 None
A0A844KSX3 18-223 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.