DPCstruct | MC11143

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)170 ± 22 aa
Standard deviation of domain lengths21.93
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score78.22
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)22.47
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A175WCR2 101-252 AAPLVTVSKSTFATSVYRLFRACLRACPTTKDMAINFVQAGQLRLQLFFSEAERLFLVHDRWLSVDGAIMELGLPDGLMEADIIFHT…
A0A7H8R6P1 6-180 NVAECKVPETPYAKNIERGLKATLALWNETNEMKMRFVSSENDDIDMAVDRKEGTLNVHQRWLKYEEMHQKHRCRELVLSDCFVCDH…
A0A2P2GWY9 394-556 None
A0A2V5IQM4 462-619 None
A0A6A5UDA5 419-576 None
Q2U1J9 9-141 None
A0A395HH48 4-168 None
A0A1V6VPU9 26-173 None
W9W285 2-165 None
A0A6A5VPX7 185-334 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.