DPCstruct | MC1111

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)220 ± 17 aa
Standard deviation of domain lengths17.26
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score95.87
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)38.46
Pfam Score91.67
Assigned Pfam label(s) PF14789- CL0536

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0A8RB60 446-681 SLFSLAFGVGTQNRQEAWLEVFYALPLLKPSSEIVAAVAPILGYAAGNQALTFTSQQAYQLADALKGIDAAQSALLSRLAESQKPLV…
S5STQ6 1-206 MTSSAYARGLATLTYDGTVLDVWYPAPKLDEPVTAAGTERLETTPQQFAALAGPDETRGVARVPVATRISDLGQAPVDAYDVYLRLH…
A0A433BG06 29-276 None
A0A160NWL1 235-445 None
A0A1I3VKF5 1-188 None
A0A3S5JIC8 129-354 None
A0A087BMY2 125-333 None
A0A2E8XIW9 4-244 None
A0A5Q2VY24 38-262 None
A0A4R3Q4S5 1-218 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.