DPCstruct | MC11023

Metacluster Properties and Pfam Annotations

Number of structural domains672
Mean domain length (aa)151 ± 28 aa
Standard deviation of domain lengths28.43
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score83.75
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)13.20
Pfam Score77.10
Assigned Pfam label(s) PF02342- CL0093- CL0128- CL0072- PF00239

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A351J3G8 5-135 TVGTGQVRIVLSWGAEPRDLDSHLWTPSDYHVYYGDEGAADASPWAWLDVDDVTSYGPETITITSVQSGTYYYSVHNYSGEHPLSQS…
A0A2M8IUS9 18-145 AERRMEERGGSRGDLNFTLEWSTTDDIDLYVTCPTGATVSYLNRGDCNGVYDLDANVLRAEAISDPVENIVFTDAPNGLYQVRAHLK…
A0A819S0W3 101-286 None
A0A538Q0Q7 42-198 None
A0A1G2VM76 28-158 None
A0A1G6Y459 6-183 None
A0A7Y5SGY9 464-603 None
A0A2G4ILR0 206-344 None
A0A820IVI9 13-134 None
A0A2P8EPB3 546-689 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.