DPCstruct | MC11016

Metacluster Properties and Pfam Annotations

Number of structural domains51
Mean domain length (aa)86 ± 7 aa
Standard deviation of domain lengths7.34
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score92.51
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.86
Mean intra-cluster local Distance Difference Test score0.85
Mean intra-cluster sequence similarity (%)49.79
Pfam Score87.30
Assigned Pfam label(s) PF02772- PF02773

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A834QDW8 277-361 MQDRGAVLPIRVHTIVVSVQHDEEVCLDEMRDALKEKVIKAVVPPKYLDEDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGG
A0A2U3XUA5 11-101 QDNGAVIPVRIHTIVISVQHNEDITLEDMRKALKEQVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGA…
W4U371 4-104 None
A0A7V6GMH7 85-160 None
A0A4W3JFH1 165-250 None
A0A5E4BJZ2 268-343 None
A0A5N5MBB6 899-981 None
A0A507FFG9 436-519 None
F0WA18 186-269 None
A0A183J7P4 204-289 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.