DPCstruct | MC10992

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)155 ± 14 aa
Standard deviation of domain lengths14.14
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score77.89
Mean fraction of residues predicted as intrinsically disordered0.61
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)39.58
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0C3NWW3 1-131 MPPRRERKPWTLPPPPGPSLRQRVEQKEREQGLRCSDTSCGIGPSDDEPYPPLSHLSMKEVSIHKQVDGAIVTSGAVCAHKFHPACL…
A0A0D7BJ99 257-392 FPMQTFVGAPPPSTRPRMPRERKKWSLPPSPGLSLREKVEKREREGGLRCDDMSCGVAPSDDDPDITVDEKRILIHRSEGGHTCAHK…
A0A0C9WFZ2 29-186 None
A0A165GKP9 404-550 None
A0A5C3QH29 1-160 None
A0A1Q3EDJ7 1001-1184 None
A0A067Q6Y4 881-1040 None
S8EMG0 631-782 None
A0A427Y384 486-648 None
A0A4S4LSF1 750-909 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.