DPCstruct | MC10973

Metacluster Properties and Pfam Annotations

Number of structural domains1227
Mean domain length (aa)157 ± 29 aa
Standard deviation of domain lengths28.52
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score83.29
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.39
Mean intra-cluster local Distance Difference Test score0.40
Mean intra-cluster sequence similarity (%)11.40
Pfam Score37.23
Assigned Pfam label(s) PF19929- PF14504- PF11006- PF03676- PF19818

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1S9AYX5 2-137 None
A0A6N2DET6 12-181 None
A0A1I4M4F3 233-377 None
A0A017RU44 239-387 None
A0A5B8LJ62 21-184 None
T4VCR9 249-388 None
A0A5Q2QFS1 12-148 None
A0A418IRF3 170-286 None
A0A1Q8QNP3 74-218 None
A0A180ENH2 5-230 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.