DPCstruct | MC10973

Metacluster Properties and Pfam Annotations

Number of structural domains1227
Mean domain length (aa)157 ± 29 aa
Standard deviation of domain lengths28.52
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score83.29
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.39
Mean intra-cluster local Distance Difference Test score0.40
Mean intra-cluster sequence similarity (%)11.40
Pfam Score37.23
Assigned Pfam label(s) PF19929- PF14504- PF11006- PF03676- PF19818

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E8RK67 4-158 None
A0A0F2Q7A8 155-306 None
H1HSB0 25-214 None
T0TM70 1-266 None
A0A5R8K9P1 25-132 None
A0A845GPC6 18-216 None
A0A669R2I7 40-200 None
A0A1F2PKV8 8-208 None
A0A6V8KJA2 377-513 None
A0A3D0XVQ6 236-431 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.